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Avogadro Goes to Court
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This case study was inspired by a successful lawsuit brought by students against a professor at Pace University who had assigned them the task of calculating the cost of a single aluminum atom in a roll of aluminum foil. The case deals with the concepts of Avogadro's number and the mole, and so would be relevant to nearly all introductory level science courses including chemistry courses for non-science majors, general science courses, and, perhaps, some introductory level biology courses in addition to general chemistry.

Author:
Frank J. Dinan
Joseph Bieron
Bacteria Are Everywhere!
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Students are introduced to the concept of engineering biological organisms and studying their growth to be able to identify periods of fast and slow growth. They learn that bacteria are found everywhere, including on the surfaces of our hands. Student groups study three different conditions under which bacteria are found and compare the growth of the individual bacteria from each source. In addition to monitoring the quantity of bacteria from differ conditions, they record the growth of bacteria over time, which is an excellent tool to study binary fission and the reproduction of unicellular organisms.

Author:
AMPS GK-12 Program,
TeachEngineering.org
Jasmin Hume
Janet Yowell
Bad Fish, Bad Bird: Neurotoxin Poisoning from Fish and Fowl
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This "clicker case" is based on the General Biology edition of James Hewlett's "Bad Fish" case in our collection. The case follows the story of biologist Dr. Westwood, who is accidentally poisoned, first while traveling in Asia and then in the South Pacific. Students learn about Dr. Westwood's experiences and about nerve cell physiology-focusing especially on the role of ion channels in maintaining and changing electrical gradients across the cell membrane (resting potential and action potentials). They then apply what they learn in each part of the case to determine the mechanism of neurotoxin poisonings described in the case. The case is presented in class via PowerPoint (~2MB). Students use personal response systems, or "clickers," to answer the multiple-choice questions that punctuate the PowerPoint presentation as they explore the underlying mechanism of Dr. Westwood's poisoning.

Author:
Kristina Hannam
Bad Fish: General Biology Edition
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In this version, developed for a course in general biology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. The General Biology Edition is designed for an introductory biology course. Its basic storyline and core objectives are carried over into a Human Anatomy& Physiology Edition and a Cell& Molecular Biology Edition, also in our collection, each of which has its own set of questions.

Author:
James A. Hewlett
Baffled by the Baby Bottle
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This case is based on an actual article entitled "Baby Alert" that appeared in Consumer Reports (May 1999). The article raises some concerns about the safety of polycarbonate baby bottles, and recommends that parents dispose of them as a precaution. However, the American Plastics Council and the Food and Drug Administration have raised concerns about the experimental methodology used as well as the recommendations made in this article. The case has been used to help develop students' critical thinking skills in an introductory chemistry course for non-majors. It may be used to illustrate applications in polymer chemistry, quantitative chemical analysis, toxicology, endocrine disruption, and risk-benefit analysis.

Author:
Michael A. Jeannot
The Balancing Act
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Students visualize and interact with concepts already learned, specifically algebraic equations and solving for unknown variables. They construct a balancing seesaw system (LEGO® Balance Scale) made from LEGO MINDSTORMS® parts and digital components to mimic a balancing scale. They are given example algebraic equation problems to analyze, configure onto the balance scale, and evaluate by manipulating LEGO pieces and gram masses that represent terms of an equation such as unknown variables, coefficients and integers. Digital light sensors, built into the LEGO Balance Scale, detect any balance or imbalances displayed on the balancing scale. The LEGO Balance Scale interactively issues a digital indication of balance or imbalance within the system. If unbalanced, students continue using the LEGO Balance Scale until they are confident in their understanding of solving algebraic equations. The goal is for students to become confident in solving algebraic equations by fundamentally understanding the basics of algebra and real-world algebraic applications.

Author:
AMPS GK-12 Program,
TeachEngineering.org
Gisselle Cunningham, Russell Holstein, Linderick Outerbridge, Jared Soto, Timothy Li
Ball Bounce Experiment
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Students investigate different balls' abilities to bounce and represent the data they collect graphically.

Author:
TeachEngineering.org
Center for Engineering Educational Outreach,
Center for Engineering Educational Outreach, Tufts University
Tufts University
Basic Chemistry Concepts Part I
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Chemistry for General Biology students. This video covers the nature of matter, elements, atomic structure and what those sneaky electrons do. AND as a bonus, I cover Lewis dot diagrams, which most of you won't see in your Gen Bio class but they will help you SO MUCH you'll wonder how you've lived without them!

Author:
ThePenguinProf
Basically Acidic Ink
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Students hypothesize whether vinegar and ammonia-based glass cleaner are acids or bases. They create designs on index cards using these substances as invisible inks. After the index cards have dried, they apply red cabbage juice as an indicator to reveal the designs.

Author:
Nicole Stewart
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Corey Burton
Christine Hawthorne
TeachEngineering.org
Rachel Howser
Basically Acids
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Students learn the basics of acid/base chemistry in a fun, interactive way by studying instances of acid/base chemistry found in popular films such as Harry Potter and the Prisoner of Azkaban and National Treasure. Students learn what acids, bases and indicators are and how they can be used, including invisible ink. They also learn how engineers use acids and bases every day to better our quality of life. Students' interest is piqued by the use of popular culture in the classroom.

Author:
TeachEngineering.org
Rachel Howser
Christine Hawthorne
University of Houston,
Begin With Buttons
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In this 8-lesson unit students use buttons to explore logical and numerical relationships that form the conceptual basis for understanding addition and subtraction operations. Topics include counting, ordinal numbers (and relative position), classification (attributes), relationships between numbers, addition of sets, commutativity of addition, sums to 10, fact families (including subtraction), three models of subtraction ("take away", comparative, missing addend), and bar graphs. Includes student activity sheets and a link to an online graphing applet.

Author:
Grace M. Burton
Beginning Scientific Inquiry with Water Kits
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This activity is a scientific investigation focusing on inquiry after using the Foss Water Kit. The students will pose a question, create a procedure and produce a poster showing their findings.

Author:
Jacquelyn Sullivan
jacquelyn sullivan
Benham's Disk
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In this optics activity, learners discover that when they rotate a special black and white pattern called a Benham's Disk, it produces the illusion of colored rings. Learners experiment with the speed of rotation and direction of rotation to observe varying patterns. Use this activity to explain to learners how our eyes detect color and how different color receptors in the eye respond at different rates.

Author:
National Science Foundation
NEC Foundation of America
California Department of Education
The Exploratorium
Don Rathjen
The Benign Hamburger
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In this dilemma case study, the executives of a popular restaurant chain must decide whether to use irradiated meat, in this case, beef, to protect its customers from the bacteria, E. coli. Students learn about food irradiation and discuss issues related to food safety and the public's acceptance of new food technologies. As developed, the case could be used in a variety of introductory science courses in chemistry, physics, biology, environmental science, and agricultural science.

Author:
Graham F. Peaslee
Juliette Lantz
Mary Walczak
Bilirubin: E-/Z-, But Not Easy
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In this case study, two students meet a professor who surprises them by telling them that a biochemically important molecule's structure has been incorrectly represented in the published literature - in an article in the Proceedings of the National Academy of Sciences, a major biochemistry textbook, and even The Merck Index. The students are challenged to find the nature of the structural errors and correct them. In addition to demonstrating that the technical literature is not without its flaws, the case reviews important concepts related to geometric isomerism and tautomerism.

Author:
Frank J. Dinan
Biochemistry
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Biochemistry is the study of the chemical processes and compounds, such as cellular makeup, that bring about life in organisms. This course will look at how these formed biomolecules interact and produce many of life's necessary processes. Also it will look at the most commonly used techniques in biochemistry research. Upon successful completion of this course, students will be able to: recognize and describe the structure of the following basic biomolecules: nucleic acids, amino acids, lipids, carbohydrates; diagram how these basic biomolecules are used as building blocks for more complex biomolecules; differentiate between reactions that create biomolecules; describe how these biomolecules are used in specific cellular pathways and processes; analyze how feedback from one pathway influences other pathways; explain how energy is utilized by a cell; indicate how biomolecules and pathways are regulated; describe how enzymes play a key role in catalysis; assess which biochemical technique should be used to study a given biochemical problem. (Biology 401; See also: Chemistry 109)

Bioinorganic Chemistry
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Exploration of the biological importance of inorganic complexes. Topics include: biochemistry and transition metal chemistry review, characterization methods, metal ion transport and cellular storage, biological electron transfer, the nitrogen cycle, oxygen transport and transfer, oxygen processing, and enzymes and proteins.

Biological Engineering Design, Spring 2010
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This course illustrates how knowledge and principles of biology, biochemistry, and engineering are integrated to create new products for societal benefit. It uses a case study format to examine recently developed products of pharmaceutical and biotechnology industries: how a product evolves from initial idea, through patents, testing, evaluation, production, and marketing. Emphasizes scientific and engineering principles; the responsibility scientists, engineers, and business executives have for the consequences of their technology; and instruction and practice in written and oral communication. The topic focus of this class will vary from year to year. This version looks at inflammation underlying many diseases, specifically its role in cancer, diabetes, and cardiovascular disease.

Author:
White, Forest
Essigmann, John
Irvine, Darrell
Breindel, Harlan
Banuazizi, Atissa
Poe, Mya
Bioorganic Chemistry
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Examination of the biological importance of organic molecules. Topics include: bioorganic mechanisms, chirality and its role in bioactivity, lipids, carbohydrates, animo acids, peptides, and porteins, nucleic acids, enzymes, coenzymes, and coupled reactions, lipid metabolism, carbohydrate metabolism, amino acid metabolism, and nucleotide metabolism.

Blue Sky
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In this optics activity, learners explore why the sky is blue and the sunset is red, using a simple setup comprising a transparent plastic box, water, and powdered milk. Learners use a flashlight to shine a beam of light through the container. Learners look at the beam from the side of the container and then from the end of the tank, and compare the colors that they see. Learners also examine a narrower beam of light. Use this activity to introduce learners to the light spectrum, wavelengths, frequency, scattering, and how all this effects what we see in the sky at different times of the day.

Author:
The Exploratorium
California Department of Education
NEC Foundation of America
National Science Foundation