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These Eyes!
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Students learn about glaucoma its causes, how it affects individuals and how biomedical engineers can identify factors that trigger or cause this eye disease, specifically the increase of pressure in the eye. Students also learn how RFID technologies transfer energy through waves and how engineers apply their scientific understanding of waves, energy and sensors to develop devices that measure the pressure in the eyes of people with glaucoma. Students conclude by sketching their own designs for a pressure-measuring eye device, preparing them to conduct the associated activity in which they revise, prototype and evaluate their device designs made tangible with a 3D printer.

Author:
Janelle Orange
Robotics Engineering for Better Life and Sustainable Future RET, College of Engineering, Michigan State University,
Using Nanoparticles to Detect, Treat and Protect against Skin Cancer
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This unit on nanoparticles engages students with a hypothetical Grand Challenge Question that asks about the skin cancer risk for someone living in Australia, given the local UV index and the condition of the region's ozone layer. The question asks how nanoparticles might be used to help detect, treat and protect people from skin cancer. Through three lessons, students learn about the science of electromagnetic radiation and energy waves, human skin and its response to ultraviolet radiation, and the state of medical nanotechnology related to skin cancer. Through three hands-on activities, students perform flame tests to become familiar with the transfer of energy in quantum form, design and conduct their own quality-control experiments to test sun protection factors (SPFs), and write nanotechnology grant proposals.

Author:
VU Bioengineering RET Program, School of Engineering, Vanderbilt University,
Michelle Bell, Amber Spolarich
We've Come a Long Way, Baby!
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Students discuss several human reproductive technologies available today pregnancy ultrasound, amniocentesis, in-vitro fertilization and labor anesthetics. They learn how each technology works, and that these are ways engineers have worked to improve the health of expecting mothers and babies.

Author:
Malinda Schaefer Zarske
Kristin Field
Integrated Teaching and Learning Program,
Denise W. Carlson
TeachEngineering.org
What Does Light See?
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Students are introduced to the concept of refraction. After making sure they understand the concepts of diffraction and interference, students work collaboratively to explain optical phenomena that cannot be accounted for via these two mechanisms alone. Then, through the associated activity, students see first-hand how refraction can work with interference to produce color patterns, similar to how nanosensors work. Finally, students apply their knowledge of refraction to the original challenge question to generate a possible solution in the form of a biosensor.

Author:
Caleb Swartz
VU Bioengineering RET Program,
What Is Going on with Grandma?
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Students are introduced to the concepts of the challenge question. First independently, and then in small groups, they generate ideas for solving the grand challenge introduced in the associated lesson: Your grandmother has a fractured hip and a BMD of -3.3. What medical diagnosis explains her condition? What are some possible causes? What are preventative measures for other family members? Students complete a worksheet that contains the pertinent questions, as well as develop additional questions of their own, all with the focus on determining what additional background knowledge they need to research. Finally, as a class, students compile their ideas, resulting in a visual as a learning supplement.

Author:
VU Bioengineering RET Program,
Morgan Evans
What Makes our Bones Strong?
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Students will use this activity to determine what keeps our bones strong. Soaking the bones in vinegar will remove the calcium from the bones causing them to become soft and rubbery. Students will find that when we age, calcium is depleted from our bones faster than we can restore it. They will then determine what complications can arise from it.

Author:
TeachEngineering.org
VU Bioengineering RET Program,
Morgan Evans (Primary Author)
When Silicon Talks
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In the first half of this two-part activity, students practice solving problems involving refraction using the index of refraction and Snell's law equations; they mathematically solve for precise angles and speeds caused by refraction. In the second half of the activity, a hands-on lab, they apply the analytical skills required by the problem set to reflectance measurements of porous silicon thin films, including how reflectance measurements would change if various aspects of the film were altered. Students predict the data output in the form of reflectance measurements when samples are altered, which connects to the idea of being able to make predictions about the data output of a biosensing thin film that couples with a target molecule.

Author:
Caleb Swartz
VU Bioengineering RET Program,
Who Robbed the Bank?
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Students use DNA profiling to determine who robbed a bank. After they learn how the FBI's Combined DNA Index System (CODIS) is used to match crime scene DNA with tissue sample DNA, students use CODIS principles and sample DNA fragments to determine which of three suspects matches evidence obtain at a crime location. They communicate their results as if they were biomedical engineers reporting to a police crime scene investigation.

Author:
Malinda Schaefer Zarske
Integrated Teaching and Learning Program,
Frank Burkholder
Denise W. Carlson
Wristwatch Design for the Visually Impaired
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Students further their understanding of the engineering design process while combining mechanical engineering and bioengineering to create assistive devices. During this extended activity (seven class periods), students are given a fictional client statement and required to follow the steps of the engineering design process (EDP) to design a new wristwatch face for a visually impaired student at their school. Student groups share their designs with the class through design presentations. A successful design meets all of the student-generated design requirements, including the development of a new method of representing time that does not require the sense of sight. Through this activity, students design, construct and iterate classroom prototypes of their watch designs.

Author:
RET Program, Department of Biomedical Engineering,
Jared Quinn, Kristen Billiar, Terri Camesano, Jeanne Hubelbank
You're the Expert
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Student teams learn about and devise technical presentations on four reproductive technology topics pregnancy ultrasound, amniocentesis, in-vitro fertilization or labor anesthetics. Each team acts as a panel of engineers asked to make a presentation to a group of students unfamiliar with the reproductive technology. Each group incorporates non-lecture elements into its presentation for greater effectiveness. As students learn about the technologies, by creating a presentation and listening to other groups' presentations, they also learn more about the valuable skill of technical communications.

Author:
Malinda Schaefer Zarske
Kristin Field
Integrated Teaching and Learning Program,
Denise W. Carlson
A Zombie Got My Leg
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Students experience the engineering design process as they design and construct lower-leg prostheses in response to a hypothetical zombie apocalypse scenario. Like the well-known Apollo 13 story during which engineers were challenged to fix the crippled spacecraft with limited supplies in order to save astronauts' lives, in this activity, students act as engineers during an imaginary disaster in which a group member's leg was amputated in order to survive a zombie attack. Building on what they learned and researched in the associated lesson, they design and fabricate a replacement prosthetic limb using given specific starting material and limited additional supplies, similar to how engineers design for individuals while working within constraints. A more-advanced scenario challenges students to design a prosthesis that is able to provide a more-specific movement function.

Author:
Megan Ketchum, Andrea Lee
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,