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Afterimage
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In this activity about light and perception, learners discover how a flash of light can create a lingering image called an "afterimage" on the retina of the eye. Learners will be surprised when they continue to see an image of a bright object after staring at it and looking away. Use this activity to introduce learners to principles of optics and perception as well as to explain why the full moon often appears larger when it is on the horizon than when it is overhead. This lesson guide also includes a few extensions like how to take "afterimage photographs."

Author:
The Exploratorium
California Department of Education
NEC Foundation of America
National Science Foundation
Anti-Gravity Mirror
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In this demonstration, amaze learners by performing simple tricks using mirrors. These tricks take advantage of how a mirror can reflect your right side so it appears to be your left side. To make the effect more dramatic, cover the mirror with a cloth, climb onto the table, straddle the mirror, and then drop the cloth as you appear to "take off." This resource contains information about how this trick was applied during the making of the movie "Star Wars."

Author:
The Exploratorium
California Department of Education
NEC Foundation of America
National Science Foundation
The Artificial Bicep
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Students learn more about how muscles work and how biomedical engineers can help keep the muscular system healthy. Following the engineering design process, they create their own biomedical device to aid in the recovery of a strained bicep. They discover the importance of rest to muscle recovery and that muscles (just like engineers!) work together to achieve a common goal.

Author:
Malinda Schaefer Zarske
Integrated Teaching and Learning Program,
Denise W. Carlson
Jonathan MacNeil
Jaime Morales
Artificial Heart Design Challenge
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Students are presented with a hypothetical scenario in which they are biomedical engineers asked to design artificial hearts. Using the engineering design process as a guide, the challenge is established and students brainstorm to list everything they might need to know about the heart in order to create a complete mechanical replacement (size, how it functions, path of blood etc.). They conduct research to learn the information and organize it through various activities. They research artificial heart models that have already been used and rate their performance in clinical trials. Finally, they analyze the data to identify the artificial heart features and properties they think work best and document their findings in essay form.

Author:
Bio-Inspired Technology and Systems (BITS) RET,
Angela D. Kolonich
Benham's Disk
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In this optics activity, learners discover that when they rotate a special black and white pattern called a Benham's Disk, it produces the illusion of colored rings. Learners experiment with the speed of rotation and direction of rotation to observe varying patterns. Use this activity to explain to learners how our eyes detect color and how different color receptors in the eye respond at different rates.

Author:
National Science Foundation
NEC Foundation of America
California Department of Education
The Exploratorium
Don Rathjen
Biomedical Devices for the Eyes
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Students examine the structure and function of the human eye, learning some amazing features about our eyes, which provide us with sight and an understanding of our surroundings. Students also learn about some common eye problems and the biomedical devices and medical procedures that resolve or help to lessen the effects of these vision deficiencies, including vision correction surgery.

Author:
William Surles
Malinda Schaefer Zarske
Integrated Teaching and Learning Program,
Denise W. Carlson
Lesley Herrmann
Biomedical Engineering and the Human Body
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Human beings are fascinating and complex living organisms a symphony of different functional systems working in concert. Through a 10-lesson series with hands-on activities students are introduced to seven systems of the human body skeletal, muscular, circulatory, respiratory, digestive, sensory, and reproductive as well as genetics. At every stage, they are also introduced to engineers' creative, real-world involvement in caring for the human body.

Author:
Integrated Teaching and Learning Program,
See individual lessons and activities.
Blue Sky
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In this optics activity, learners explore why the sky is blue and the sunset is red, using a simple setup comprising a transparent plastic box, water, and powdered milk. Learners use a flashlight to shine a beam of light through the container. Learners look at the beam from the side of the container and then from the end of the tank, and compare the colors that they see. Learners also examine a narrower beam of light. Use this activity to introduce learners to the light spectrum, wavelengths, frequency, scattering, and how all this effects what we see in the sky at different times of the day.

Author:
The Exploratorium
California Department of Education
NEC Foundation of America
National Science Foundation
Body Full of Crystals
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Students learn about various crystals, such as kidney stones, within the human body. They also learn about how crystals grow and ways to inhibit their growth. They also learn how researchers such as chemical engineers design drugs with the intent to inhibit crystal growth for medical treatment purposes and the factors they face when attempting to implement their designs. A day before presenting this lesson to students, conduct the associated activity, Rock Candy Your Body.

Author:
Andrea Lee, Megan Ketchum
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs, University of Houston,
Bone Crusher
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Students use a tension-compression machine (or an alternative bone-breaking setup) to see how different bones fracture differently and with different amounts of force, depending on their body locations. Teams determine bone mass and volume, calculate bone density, and predict fracture force. Then they each test a small animal bone (chicken, turkey, cat) to failure, examining the break to analyze the fracture type. Groups conduct research about biomedical challenges, materials and repair methods, and design repair treatment plans specific to their bones and fracture types, presenting their design recommendations to the class.

Author:
Andrea Lee, Megan Ketchum
National Science Foundation GK-12 and Research Experience for Teachers (RET) Programs,
Bone Fractures and Engineering
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Students learn about the role engineers and engineering play in repairing severe bone fractures. They acquire knowledge about the design and development of implant rods, pins, plates, screws and bone grafts. They learn about materials science, biocompatibility and minimally-invasive surgery.

Author:
Integrated Teaching and Learning Program, College of Engineering,
Todd Curtis, Malinda Schaefer Zarske, Janet Yowell, Denise W. Carlson
Bone Stress
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In this optics activity, learners examine how polarized light can reveal stress patterns in clear plastic. Learners place a fork between two pieces of polarizing material and induce stress by squeezing the tines together. Learners will observe the colored stress pattern in the image of the plastic that is projected onto a screen using an overhead projector. Learners rotate one of the polarizing filters to explore which orientations give the most dramatic color effects. This activity can be related to bones, as bones develop stress patterns from the loads imposed upon them every day.

Author:
The Exploratorium
California Department of Education
NEC Foundation of America
National Science Foundation
Bones! Bones! Bones!
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After learning, comparing and contrasting the steps of the engineering design process (EDP) and scientific method, students review the human skeletal system, including the major bones, bone types, bone functions and bone tissues, as well as other details about bone composition. Students then pair-read an article about bones and bone growth and compile their notes to summarize the article. Finally, students complete a homework assignment to review the major bones in the human body, preparing them for the associated activities in which they create and test prototype replacement bones with appropriate densities. Two PowerPoint(TM) presentations, pre-/post-test, handout and worksheet are provided.

Author:
Michelle Gallagher, Terri Camesano, Jeanne Hubelbank, Kristen Billiar, Dua Chaker, Carleigh Samson
Inquiry-Based Bioengineering Research and Design Experiences for Middle-School Teachers RET Program, Department of Biomedical Engineering, Worcester Polytechnic Institute,
Brain is a Computer
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Students learn about the similarities between the human brain and its engineering counterpart, the computer. Since students work with computers routinely, this comparison strengthens their understanding of both how the brain works and how it parallels that of a computer. Students are also introduced to the "stimulus-sensor-coordinator-effector-response" framework for understanding human and robot actions.

Author:
GK-12 Program, Computational Neurobiology Center,
Sachin Nair, Charlie Franklin, Satish Nair
Breathe In, Breathe Out
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Students are introduced to the respiratory system, the lungs and air. They learn about how the lungs and diaphragm work, how air pollution affects lungs and respiratory functions, some widespread respiratory problems, and how engineers help us stay healthy by designing machines and medicines that support respiratory health and function.

Author:
Malinda Schaefer Zarske
Jay Shah
Integrated Teaching and Learning Program,
Denise W. Carlson
Can It Support You? No Bones about It!
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After completing the associated lesson and its first associated activity, students are familiar with the 20 major bones in the human body knowing their locations and relative densities. When those bones break, lose their densities or are destroyed, we look to biomedical engineers to provide replacements. In this activity, student pairs are challenged to choose materials and create prototypes that could replace specific bones. They follow the steps of the engineering design process, researching, brainstorming, prototyping and testing to find bone replacement solutions. Specifically, they focus on identifying substances that when combined into a creative design might provide the same density (and thus strength and support) as their natural counterparts. After iterations to improve their designs, they present their bone alternative solutions to the rest of the class. They refer to the measured and calculated densities for fabricated human bones calculated in the previous activity, and conduct Internet research to learn the densities of given fabrication materials (or measure/calculate those densities if not found online).

Author:
Michelle Gallagher, Terri Camesano, Jeanne Hubelbank, Kristen Billiar
Inquiry-Based Bioengineering Research and Design Experiences for Middle-School Teachers RET Program, Department of Biomedical Engineering, Worcester Polytechnic Institute,
Cereal Magnets
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Student groups compete to design a process that removes the most iron from fortified cereal. Students experiment with different materials using what they know about iron, magnets and forces to design the best process for removing iron from the cereal samples.

Author:
Engineering K-PhD Program,
Liz Harper
Clearing a Path to the Heart
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Following the steps of the engineering design process and acting as biomedical engineers, student teams use everyday materials to design and develop devices and approaches to unclog blood vessels. Through this open-ended design project, they learn about the circulatory system, biomedical engineering, and conditions that lead to heart attacks and strokes.

Author:
Todd Curtis
Malinda Schaefer Zarske
Integrated Teaching and Learning Program,
Denise W. Carlson
Jay Shah
Commanding a Robot Using Sound
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Students continue their exploration of the human senses and their engineering counterparts, focusing on the auditory sense. Working in small groups, students design, create and run programs to control the motion of LEGO® TaskBots. By doing this, they increase their understanding of the use and function of sound sensors, gain experience writing robot programs, and reinforce their understanding of the sensory process.

Author:
GK-12 Program, Computational Neurobiology Center, College of Engineering,
Sachin Nair, Kalyani Upendram, Satish Nair
Control Using Sound
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Students gain a deeper understanding of how sound sensors work through a hands-on design challenge involving LEGO MINDSTORMS(TM) NXT taskbots and sound sensors. Student groups each program a robot computer to use to the sound of hand claps to control the robot's movement. They learn programming skills and logic design in parallel. They experience how robots can take sensor input and use it to make decisions to move and turn, similar to the human sense of hearing. A PowerPoint® presentation and pre/post quizzes are provided.

Author:
Srijith Nair, Pranit Samarth, Satish S. Nair
GK-12 Program, Computational Neurobiology Center,