This course introduces students to the principles, laws, and policies that influence the use of animal and alternative, non-animal-based (humane sciences) research techniques in biomedical research.
- Author:
- Paul A. Locke
- Alan M. Goldberg
This course introduces students to the principles, laws, and policies that influence the use of animal and alternative, non-animal-based (humane sciences) research techniques in biomedical research.
As an expert on cutting-edge digital displays, Mary Lou Jepsen studies how to show our most creative ideas on screens. And as a brain surgery patient herself, she is driven to know more about the neural activity that underlies invention, creativity, thought. She meshes these two passions in a rather mind-blowing talk on two cutting-edge brain studies that might point to a new frontier in understanding how (and what) we think.
This course Introduces students to ethics concepts as they apply to questions and challenges in conducting human subject research. The aim is to increase students' knowledge and skills to recognize and consider ethical issues that arise in the conduct of human subject research. The course was designed for clinical investigators in India who will likely collaborate with US investigators; it therefore includes a discussion of US and Indian regulatory requirements relevant to the conduct of collaborative research.
This course introduces mental health as an integral part of global health research, including conducting needs assessments and intervention monitoring and evaluation. Presents and critiques strategies for integrating local cultural perspectives into research models. Examines methods of adapting psychiatric assessment tools for use cross-culturally and presents challenges for developing interventions for use in low-resource contexts. Encourages use of critical and creative thinking skills throughout to discuss the issues involved in this relatively new area of study.
This course leads participants through the process of designing their own survey. Examines the major decisions faced by a health researcher who wants to design and implement a survey. Explores the potential sources of bias associated with alternative approaches to sample design, respondent recruitment, data collection methods (interviews in-person or by telephone, computer assisted interviews, or mail surveys) instrument design, and field administration. Participants prepare a defensible proposal for a survey that they would like to conduct. Emphasizes population surveys, but not exclusively so.
Students learn about the biomedical use of nanoparticles in the detection and treatment of cancer, including the use of quantum dots and lasers that heat-activate nanoparticles. They also learn about electrophoresis a laboratory procedure that uses an electric field to move tiny particles through a channel in order to separate them by size. They complete an online virtual mini-lab, with accompanying worksheet, to better understand gel electrophoresis. This prepares them for the associated activity to write draft research proposals to use nanoparticles to protect against, detect or treat skin cancer.
Laboratory or field work in earth, atmospheric, and planetary sciences. To be arranged with department faculty. Consult with department Education Office. This course introduces fundamentals of radon physics, geology, radiation biology; provides hands on experience of measurement of radon in MIT environments, and discusses current radon research in the fields of geology, environment, building and construction, medicine and health physics.
Provides graduate students and fellows with techniques that enhance both validity and responsible conduct in scientific practice. Topics include study design, laboratory practice, treatment of data, human and animal research, intellectual property, preparation of proposals, research papers, posters, and oral presentations. Also discussed are mentoring relationships and career options. Aspects of responsible research conduct are integrated as appropriate to the specific topic under discussion. Subject satisfies the training grant requirements of the NIH for education in the responsible conduct of research. This course is designed to provide graduate students and postdoctoral associates with techniques that enhance both validity and responsible conduct in scientific practice. Lectures present practical steps for developing skills in scientific research and are combined with discussion of cases. The course covers study design, preparation of proposals and manuscripts, peer review, authorship, use of humans and non-human animals in research, allegations of misconduct, and intellectual property. Also discussed are mentoring relationships and career options. Aspects of responsible research conduct are integrated into lectures and case discussion as appropriate to the specific topic. This course also satisfies the training grant requirements of the NIH for education in the responsible conduct of research.