This case study introduces students to treatment alternatives for depression using a jigsaw method in which groups of students are divided up so that each member of the "home group" becomes the "resident expert" in one of five possible treatment options. Designed for a course in abnormal psychology, this case could be adapted for courses in physiological psychology, pharmacy, and neurobiology.
Students learn about the similarities between the human brain and its engineering counterpart, the computer. Since students work with computers routinely, this comparison strengthens their understanding of both how the brain works and how it parallels that of a computer. Students are also introduced to the "stimulus-sensor-coordinator-effector-response" framework for understanding human and robot actions.
Since caffeine is a widely used substance, especially by college age students, this case on the effects of caffeine on the human body serves as a real-world connection to many students' lives. The case is divided into sections covering background information on caffeine, cell biology and signal transduction, Parkinson's disease, cardiovascular effects, and addiction/withdrawal. The case was designed so that a section can be used alone or in combination with other sections, as dictated by topic/curriculum needs. It would be appropriate for use in a variety of science and health related courses, including anatomy and physiology, disease related courses, genetics, cell biology, molecular biology, biochemistry, and neuroscience.
This course has been designed as a seminar to give students an understanding of how scientists with medical or scientific degrees conduct research in both hospital and academic settings. There will be interactive discussions with research clinicians and scientists about the career opportunities and research challenges in the biomedical field, which an MIT student might prepare for by obtaining an MD, PhD, or combined degrees. The seminar will be held in a case presentation format, with topics chosen from the radiological sciences, including current research in magnetic resonance imaging, positron emission tomography and other nuclear imaging techniques, and advances in radiation therapy. With the lectures as background, we will also examine alternative and related options such as biomedical engineering, medical physics, and medical engineering. We'll use as examples and points of comparisons the curriculum paths available through MIT's Department of Nuclear Science and Engineering. In past years we have given very modest assignments such as readings in advance of or after a seminar, and a short term project.
This discussion case explores the scientific process involved in implementing an animal model in the study of Alzheimer's disease. Students read a short paragraph describing a study in which the brains of "trained" mice were injected with beta-amyloid fragments, which subsequently caused them to forget their tasks. The paragraph is a very short New York Times story reporting on an experimental study originally published in the Proceedings of the National Academy of Sciences. Based on the short description provided, students are asked to identify relevant components of the scientific method (problem, method, results, and conclusions). The case is suitable for a wide variety of science majors and non-majors courses.
"Samuel Dexter" is 52 years old, overweight, and a heavy smoker. He wakes one morning with weakness on his right side. When he attempts to walk to the bathroom, he stumbles and then falls. His wife, who suspects he has suffered a stroke, calls 911. Students read the short case scenario, including a brief clinical history of the patient and description of his injury, then answer a set of directed questions designed to probe the students' knowledge of the anatomy, physiology, and pathology underlying the patient's condition. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.
"Melanie Johnson" is a 32-year-old accountant who has moved to Green Bay, Wisconsin, from her hometown of Sarasota, Florida. For the first time in her life, she has been experiencing periods of depression, lethargy, and excessive sleeping. Students read about these symptoms then answer a set of directed questions designed to teach facts and principles of anatomy and physiology using reference books, textbooks, the Internet, and each other as sources of information. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.
"Jason Hendrix," a 21-year-old student majoring in economics, is injured in a serious motorcycle accident while on spring break in Florida. Students read the short case scenario, which provides a brief clinical history of the patient and a description of his injury, then answer a set of directed questions designed to probe the students' knowledge of the anatomy, physiology, and pathology underlying the patient's condition. The case study has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.
"Rollie Hendrix," a 35-year-old husband and father of three children, has been experiencing headaches and palpitations of increasing frequency and severity over the past six months. In addition, he has had periods of intense anxiety and panic attacks. Students read about these symptoms and then answer a set of directed questions designed to teach facts and principles of anatomy and physiology using reference books, textbooks, the Internet, and each other as sources of information. The case has been used in both a sophomore-level course in human anatomy and physiology and a senior-level course in general physiology.
Students continue their exploration of the human senses and their engineering counterparts, focusing on the auditory sense. Working in small groups, students design, create and run programs to control the motion of LEGO® TaskBots. By doing this, they increase their understanding of the use and function of sound sensors, gain experience writing robot programs, and reinforce their understanding of the sensory process.
Introduction to the use of computers to automate data analysis or model hypotheses in the field of biology, and its application for molecular and cellular biology, biochemistry, neuroscience and evolution.
Students gain a deeper understanding of how sound sensors work through a hands-on design challenge involving LEGO MINDSTORMS(TM) NXT taskbots and sound sensors. Student groups each program a robot computer to use to the sound of hand claps to control the robot's movement. They learn programming skills and logic design in parallel. They experience how robots can take sensor input and use it to make decisions to move and turn, similar to the human sense of hearing. A PowerPoint® presentation and pre/post quizzes are provided.
As an expert on cutting-edge digital displays, Mary Lou Jepsen studies how to show our most creative ideas on screens. And as a brain surgery patient herself, she is driven to know more about the neural activity that underlies invention, creativity, thought. She meshes these two passions in a rather mind-blowing talk on two cutting-edge brain studies that might point to a new frontier in understanding how (and what) we think.
Students' understanding of how robotic ultrasonic sensors work is reinforced in a design challenge involving LEGO MINDSTORMS(TM) NXT robots and ultrasonic sensors. Student groups program their robots to move freely without bumping into obstacles (toy LEGO people). They practice and learn programming skills and logic design in parallel. They see how robots take input from ultrasonic sensors and use it to make decisions to move, resulting in behavior similar to the human sense of sight but through the use of sound sensors, more like echolocation. Students design-test-redesign-retest to achieve successful programs. A PowerPoint® presentation and pre/post quizzes are provided.
In this case, students assume the role of a fictitious space explorer captured by aliens. To win their release, they must correctly explain the neurophysiology underlying some of the punishments used by the aliens to deter attempts at escape. The purpose of the case is two-fold. First, it strengthens students' understanding of ion channel function to the point where they are able to make predictions about the ability of the cell to generate an action potential if the activity of a particular ion channel is altered. Second, students are encouraged to place neuronal signaling in a larger context by hypothesizing how altered activity in a specified region or division of the nervous system will be manifested in physical symptoms. While written for a two-semester anatomy and physiology course, this case would also be useful in an undergraduate physiology or neuroscience course or in any course in which students must gain an understanding of foundational neurophysiology.
Students' understanding of how robotic light sensors work is reinforced in a design challenge involving LEGO MINDSTORMS(TM) NXT robots and light sensors. Working in pairs, students program LEGO robots to follow a flashlight as its light beam moves around. Students practice and learn programming skills and logic design in parallel. They see how robots take input from light sensors and use it to make decisions to move, similar to the human sense of sight. Students also see how they perform the steps of the engineering design process in the course of designing and testing to achieve a successful program. A PowerPoint® presentation and pre/post quizzes are provided.
A fight in a college town bar between the football player of one team and a drunken fan of a rival team results in a serious spinal cord injury. Students working in groups read the case and research the questions associated with it, which they then discuss in class. The case was designed to help pharmacy students understand the architecture of the central nervous system, its major motor/sensory tracts, the signs/symptoms of motor and sensory tract lesions, and the treatment of spinal cord injuries. It could be used in any course in which students have a basic knowledge of integrative physiology and have been exposed to the immune system, nervous system, and cardiovascular system, such as an undergraduate neuroscience course.
Students learn about the anatomy of the ear and how the ears work as a sound sensor. Ear anatomy parts and structures are explained in detail, as well as how sound is transmitted mechanically and then electrically through them to the brain. Students use LEGO® robots with sound sensors to measure sound intensities, learning how the NXT brick (computer) converts the intensity of sound measured by the sensor input into a number that transmits to a screen. They build on their experiences from the previous activities and establish a rich understanding of the sound sensor and its relationship to the TaskBot's computer.
This lesson highlights the similarities between human sensors and their engineering counterparts. Taking this approach enables students to view the human body as a system, that is, from the perspective of an engineer. Humans have recreated most human sensors in robots – eyes, ears and sensors for temperature, touch and smell. The lesson inculdes a PowerPoint file that is programmed to run a Jeopardy-style game as a fun assessment tool.
Students learn more about how light sensors work, reinforcing their similarities to the human sense of sight. They look at the light sensing process incoming light converted to electrical signals sent to the brain through the human eye anatomy as well as human-made electrical light sensors. A mini-activity, which uses LEGO MINDSTORMS(TM) NXT intelligent bricks and light sensors gives students a chance to investigate how light sensors function in preparation for the associated activity involving the light sensors and taskbots. A PowerPoint® presentation explains stimulus-to-response pathways, sensor fundamentals, and details about the LEGO light sensor, including its two modes of gathering data and what its numerical value readings mean. Students take pre/post quizzes and watch a short online video. This lesson and its associated activity enable students to gain a deeper understanding of how robots can take sensor input and use it to make decisions via programming.