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Let the Blood Flow
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Students work as biomedical engineers to find liquid solutions that can clear away polyvinyl acetate polymer "blood clots" in model arteries (made of clear, flexible tubing). Teams create samples of the "blood clot" polymer with different concentrations to discover the concentration of the model clot and then test a variety of liquids to determine which most effectively breaks down the model blood clot. Students learn the importance of the testing phase in the engineering design process, because they are only given one chance to present the team's solution and apply it to the model blood clot.

Author:
Science and Engineering of the Environment of Los Angeles (SEE-LA) GK-12 Program,
Azim Laiwalla, Ann McCabe, Carleigh Samson
Living with Your Liver
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Students learn the function of the liver and how biomedical engineers can use liver regeneration to help people. Students test the effects of toxic chemicals on a beef liver by adding hydrogen peroxide to various liver and salt solutions. They observe, record and graph their results.

Author:
Malinda Schaefer Zarske
Integrated Teaching and Learning Program,
Megan Schroeder
Denise W. Carlson
Making Model Microfluidic Devices Using JELL-O
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Students create large-scale models of microfluidic devices using a process similar to that of the PDMS and plasma bonding that is used in the creation of lab-on-a-chip devices. They use disposable foam plates, plastic bendable straws and gelatin dessert mix. After the molds have hardened overnight, they use plastic syringes to inject their model devices with colored fluid to test various flow rates. From what they learn, students are able to answer the challenge question presented in lesson 1 of this unit by writing individual explanation statements.

Author:
TeachEngineering.org
Michelle Woods (primary author)
VU Bioengineering RET Program,
Microfluidic Devices and Flow Rate
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Students obtain a basic understanding of microfluidic devices, how they are developed and their uses in the medical field. After conducting the associated activity, they watch a video clip and learn about flow rate and how this relates to the speed at which medicine takes effect in the body. What they learn contributes to their ongoing objective to answer the challenge question presented in lesson 1 of this unit. They conclude by solving flow rate problems provided on a worksheet.

Author:
TeachEngineering.org
VU Bioengineering RET Program,
Michelle Woods
Model Heart Valves
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Students use provided materials to design and build prototype artificial heart valves. Their functioning is demonstrated using water to simulate the flow of blood through the heart. Upon completion, teams demonstrate their fully functional prototypes to the rest of the class, along with a pamphlet that describes the device and how it works.

Author:
Carleigh Samson
Michael Duplessis
VU Bioengineering RET Program,
Janet Yowell
Optimize! Cleaner Energy Options for Rural China
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Students work in engineering teams to optimize cleaner energy solutions for cooking and heating in rural China. They choose between various options for heating, cooking, hot water, and lights and other electricity, balancing between the cost and health effects of different energy choices.

Author:
Abigail T. Watrous, Stephanie Rivale, Janet Yowell, Denise W. Carlson (This material developed in part during Watrous' China Fulbright fellowship in 2009-10. Sincere thanks to the U.S. State Department and the Fulbright Program for their support.)
Integrated Teaching and Learning Program,
Optimizing Your Diet: What Linear Programming Can Tell You
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In this video lesson, students will learn about linear programming (LP) and will solve an LP problem using the graphical method. Its focus is on the famous "Stigler's diet" problem posed by the 1982 Nobel Laureate in economics, George Stigler. Based on his problem, students will formulate their own diet problem and solve it using the graphical method. The prerequisites to this lesson are basic algebra and geometry. The materials needed for the in-class activities include graphing paper and pencil. This lesson can be completed in one class of approximately one hour. If the teacher would like to cover the simplex algorithm by George Dantzig as an alternative solution method, an additional whole class period is suggested.

Author:
Aysegul Topcu
Panoptes and the Bionic Eye
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Vision is the primary sense of many animals and much is known about how vision is processed in the mammalian nervous system. One distinct property of the primary visual cortex is a highly organized pattern of sensitivity to location and orientation of objects in the visual field. But how did we learn this? An important tool is the ability to design experiments to map out the structure and response of a system such as vision. In this activity, students learn about the visual system and then conduct a model experiment to map the visual field response of a Panoptes robot. (In Greek mythology, Argus Panoptes was the "all-seeing" watchman giant with 100 eyes.) A simple activity modification enables a true black box experiment, in which students do not directly observe how the visual system is configured, and must match the input to the output in order to reconstruct the unseen system inside the box.

Author:
Michael Trumpis, Shingi Middelmann, Gisselle Cunningham
AMPS GK-12 Program, Polytechnic Institute of New York University,
Participation Skills & Techniques Q2
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Participation Skills and Techniques is designed to help students learn the techniques and skills necessary to participate effectively in a variety of games and activities. Students will learn to participate in activities designed to improve balance, flexibility, strength, endurance and teamwork. The goal of this class is to provide knowledge, resources and activities designed to promote personal responsibility in developing a healthy lifestyle through combining fitness and cardio. Students will be empowered to make choices, meet challenges and develop positive behaviors in fitness, wellness and movement activity for a lifetime. Emphasis is placed on students analyzing skills for effective movement. This is the second part of a two-quarter course.

Pill Dissolving Demo
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In a class demonstration, the teacher places different pill types ("chalk" pill, gel pill, and gel tablet) into separate glass beakers of vinegar, representing human stomach acid. After 20-30 minutes, the pills dissolve. Students observe which dissolve the fastest, and discuss the remnants of the various pills. What they learn contributes to their ongoing objective to answer the challenge question presented in lesson 1 of this unit.

Author:
TeachEngineering.org
Michelle Woods (primary author)
VU Bioengineering RET Program,
Principles of Human Nutrition
Conditional Remix & Share Permitted
CC BY-NC-SA
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Principles of Human Nutrition (222.641) provides an integrated overview of the physiological requirements and functions of protein, energy, and the major vitamins and minerals that are determinants of health and diseases in human populations. Topics include the following: Dietary sources, intake levels, physiological role, and requirement of major nutrients; The biological determinants of nutrient requirements and the assessment of nutrient status in individuals and populations; The role of nutrition in growth and health through the life cycle; The rationale for the development of dietary guidelines and of nutrition policies in different countries; The role of diet in the development of chronic diseases, such as cardiovascular disease, cancer, diabetes, etc.

Subject:
Life Science
Nutrition
Material Type:
Full Course
Lecture Notes
Syllabus
Author:
Caballero, Benjamin
Date Added:
02/16/2011
Protect Your Body, Filter Your Water!
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Students experience the steps of the engineering design process as they design solutions for a real-world problem that could affect their health. After a quick review of the treatment processes that municipal water goes through before it comes from the tap, they learn about the still-present measurable contamination of drinking water due to anthropogenic (human-made) chemicals. Substances such as prescription medication, pesticides and hormones are detected in the drinking water supplies of American and European metropolitan cities. Using chlorine as a proxy for estrogen and other drugs found in water, student groups design and test prototype devices that remove the contamination as efficiently and effectively as possible. They use plastic tubing and assorted materials such as activated carbon, cotton balls, felt and cloth to create filters with the capability to regulate water flow to optimize the cleaning effect. They use water quality test strips to assess their success and redesign for improvement. They conclude by writing comprehensive summary design reports.

Author:
Timothy S. Vaillancourt, Terri Camesano, Kristen Billiar, Jeanne Hubelbank
Inquiry-Based Bioengineering Research and Design Experiences for Middle-School Teachers RET Program, Department of Biomedical Engineering, Worcester Polytechnic Institute,
Proteomics
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The goal of proteomics is to analyze the varying proteomes of an organism at different times, in order to highlight differences between them. Put more simply, proteomics analyzes the structure and function of biological systems. [8] For example, the protein content of a cancerous cell is often different from that of a healthy cell. Certain proteins in the cancerous cell may not be present in the healthy cell, making these unique proteins good targets for anti-cancer drugs. The realization of this goal is difficult; both purification and identification of proteins in any organism can be hindered by a multitude of biological and environmental factors. [9]

Rural Energy in China: How Can Engineers Make a Difference?
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Students learn about five types of renewable energy that are part of engineering solutions to help people in rural communities use less and cleaner energy for cooking and heating. Specifically, students learn about the pollution and health challenges facing families in rural China, and they are introduced to the concept of optimization. Through an energy game, students differentiate between renewable and non-renewable sources of energy.

Author:
Abigail T. Watrous, Stephanie Rivale, Janet Yowell, Denise W. Carlson (This material developed in part during Watrous' China Fulbright fellowship in 2009-10. Sincere thanks to the U.S. State Department and the Fulbright Program for their support.)
Integrated Teaching and Learning Program,
Saving a Life: Heart Valve Replacement
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Students use their knowledge about how healthy heart valves function to design, construct and implant prototype replacement mitral valves for hypothetical patients' hearts. Building on what they learned in the associated lesson about artificial heart valves, combined with the testing and scoring of their prototype heart valve designs in this activity, students discover the pros and cons of different types of artificial heart valves based on materials, surgery requirements, and lifespan.

Author:
Integrated Teaching and Learning Program,
Brandi Briggs
Denise W. Carlson
Ben Terry
Carleigh Samson
The Science Essay, Spring 2009
Conditional Remix & Share Permitted
CC BY-NC-SA
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" The science essay uses science to think about the human condition; it uses humanistic thinking to reflect on the possibilities and limits of science and technology. In this class we read and practice writing science essays of varied lengths and purposes. We will read a wide variety of science essays, ranging across disciplines, both to learn more about this genre and to inspire your own writing. This semester's reading centers on "The Dark Side," with essays ranging from Alan Lightman's "Prisoner of the Wired World" through Robin Marantz Henig's cautionary account of nano-technology ("Our Silver-Coated Future") to David Quammen's investigation of diseases that jump from animals to humans ("Deadly Contact")."

Subject:
Arts and Humanities
Business and Communication
Ecology
Education
Educational Technology
Journalism
Life Science
World Cultures
Material Type:
Full Course
Textbook
Author:
Boiko, Karen
Date Added:
01/01/2009
Sensors and Scatterplots
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Students are introduced to several types of common medical sensor devices, such as ear and forehead thermometers, glucometers and wrist blood pressure monitors; they use the latter to measure their blood pressure and pulse rates. Students also measure their heights and weights in order to calculate their BMIs (body mass index). Then they use the collected data to create and analyze scatterplots of the different variables to determine if any relationships exist between the measured variables. Discussions about the trends observed and possible health concerns conclude the activity.

Author:
Elma M. Piñon, Mounir Ben Ghalia
RET-ENET Program,
Simulation in Healthcare
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Students learn how engineering design is applied to solve healthcare problems by using an engineering tool called simulation. While engineering design is commonly used to study and design everything from bridges, factories, airports to space shuttles, the use of engineering design to study healthcare administration and delivery is a relatively new concept.

Author:
Courtney Feliciani (under the advisement of Patricio Rocha, Dayna Martinez and Tapas K. Das)
STARS GK-12 Program,
Skeletal System
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Through this unit, written for an honors anatomy and physiology class, students become familiar with the human skeletal system and answer the Challenge Question: When you get home from school, your mother grabs you, and you race to the hospital. Your grandmother fell and was rushed to the emergency room. The doctor tells your family your grandmother has a fractured hip, and she is referring her to an orthopedic specialist. The orthopedic doctor decides to perform a DEXA scan. The result show her BMD is -3.3. What would be a probable diagnosis to her condition? What are some possible causes of her condition? Should her daughter and granddaughter be worried about this condition, and if so, what are measures they could take to prevent this from happening to them?

Author:
VU Bioengineering RET Program,
TeachEngineering.org
Morgan R. Evans
Surgical Device Engineering
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This unit focuses on teaching students about the many aspects of biomedical engineering (BME). Students come to see that BME is a broad field that relies on concepts from many engineering disciplines. They also begin to understand some of the special considerations that must be made when dealing with the human body. Activities and class discussions encourage students to think as engineers to come up with their own solutions to some of medical challenges that have been solved throughout the history of BME. Class time iincludes brainstorming and presenting ideas to the class for discussion. Specific activities include examination of the material properties and functions of surgical instruments and prosthetics, a simulation of the training experience of a surgical resident, and an investigation of the properties of fluid flow in vascular tissue.

Author:
Alice Hammer
Emily McDowell
Techtronics Program,