"This course provides a thorough introduction to the C programming language, the workhorse of the UNIX operating system and lingua franca of embedded processors and micro-controllers. The first two weeks will cover basic syntax and grammar, and expose students to practical programming techniques. The remaining lectures will focus on more advanced concepts, such as dynamic memory allocation, concurrency and synchronization, UNIX signals and process control, library development and usage. Daily programming Assignments and Labs and weekly laboratory exercises are required. Knowledge of C is highly marketable for summer internships, UROPs, and full-time positions in software and embedded systems development."

This course focuses on the historical problems and interventions associated with infant mortality. Describes the scientific basis for infant mortality and analyzes causes and consequences in a population and development of a programmatic and policy approach.

Subject provides a comprehensive overview of human pathology with emphasis on mechanisms of disease and modern diagnostic technologies. Topics include: general mechanisms of disease (inflammation, infection, immune injury, host response to foreign materials, transplantation, genetic disorders and neoplasia); pathology of lipids, enzymes, and molecular transporters; pathology of major organ systems; and review of diagnostic tools from invasive surgical pathology to non-invasive techniques such as optical spectroscopy, functional imaging, and molecular markers of disease. The objectives of this subject are achieved by a set of integrated lectures and laboratories, as well as a student-driven term project leading to a formal presentation on a medical, socioeconomic, or technological issue in human pathology.

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

The principles and practice of tissue engineering (and regenerative medicine) are taught by faculty of the Harvard-MIT Division of Health Sciences and Technology (HST) and Tsinghua University, Beijing, China. The principles underlying strategies for employing selected cells, biomaterial scaffolds, soluble regulators or their genes, and mechanical loading and culture conditions, for the regeneration of tissues and organs in vitro and in vivo are addressed. Differentiated cell types and stem cells are compared and contrasted for this application, as are natural and synthetic scaffolds. Methodology for the preparation of cells and scaffolds in practice is described. The rationale for employing selected growth factors is covered and the techniques for incorporating their genes into the scaffolds are examined. Discussion also addresses the influence of environmental factors including mechanical loading and culture conditions (e.g., static versus dynamic). Methods for fabricating tissue-engineered products and devices for implantation are taught. Examples of tissue engineering-based procedures currently employed clinically are analyzed as case studies.

Deals with more advanced design theories and textual analysis. Emphasis on script analysis in general, as well as from a designer's perspective. Students also refine technical skills in rendering and presentation, historical research, and analysis. Class sessions include interaction with student/faculty directors and other staff designers. Goal is for students to approach text with a fresh vision and translate that vision into design for performance.

Coding for the AWGN channel; block and convolutional codes; lattice and trellis codes; capacity-approaching codes; equalization of linear Gaussian channels; linear, decision-feedback, and MLSD equalization; precoding; multicarrier modulation; and topics in wireless communication.

Presents principles underlying preclinical and clinical development of new therapeutic drugs and procedures. Describes and evaluates specific examples, and discusses legal and ethical regulations that apply to drug development.

Covers current understanding of and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Specific topics include the genetics of simple and complex traits; Karyotypic analysis and positional cloning; genetic diagnosis; the roles of oncogenes and tumor suppressors in tumor initiation, progression and treatment; the interaction between genetics and environment; animal models of human disease; cancer; and conventional and gene therapy treatment strategies.

Principles of Human Nutrition (222.641) provides an integrated overview of the physiological requirements and functions of protein, energy, and the major vitamins and minerals that are determinants of health and diseases in human populations. Topics include the following: Dietary sources, intake levels, physiological role, and requirement of major nutrients; The biological determinants of nutrient requirements and the assessment of nutrient status in individuals and populations; The role of nutrition in growth and health through the life cycle; The rationale for the development of dietary guidelines and of nutrition policies in different countries; The role of diet in the development of chronic diseases, such as cardiovascular disease, cancer, diabetes, etc.

Principles of Industrial Hygiene provides an introduction to the field of industrial hygiene and to occupational health in general. The instructor focuses on introducing concepts, terminology, and methodology in the practice of industrial hygiene and identifies resource materials. The class would benefit those wishing to pursue a Master's degree in industrial hygiene, those wishing to complete a certificate in occupational health, or for students in allied health fields needing a basic understanding of industrial hygiene.

" This course provides a systematic presentation of the chemical applications of group theory with emphasis on the formal development of the subject and its applications to the physical methods of inorganic chemical compounds. Against the backdrop of electronic structure, the electronic, vibrational, and magnetic properties of transition metal complexes are presented and their investigation by the appropriate spectroscopy described."

This course covers the principles of main group (s and p block) element chemistry with an emphasis on synthesis, structure, bonding, and reaction mechanisms.

" An introduction to the principles of tomographic imaging and its applications. It includes a series of lectures with a parallel set of recitations that provide demonstrations of basic principles. Both ionizing and non-ionizing radiation are covered, including x-ray, PET, MRI, and ultrasound. Emphasis on the physics and engineering of image formation."

This course presents principles of naval architecture, ship geometry, hydrostatics, calculation and drawing of curves of form, intact and damage stability, hull structure strength calculations and ship resistance. It introduces computer-aided naval ship design and analysis tools. Projects include analysis of ship lines drawings, calculation of ship hydrostatic characteristics, analysis of intact and damaged stability, ship model testing, and hull structure strength calculations.

This course introduces theoretical and practical principles of design of oceanographic sensor systems. Topics include: transducer characteristics for acoustic, current, temperature, pressure, electric, magnetic, gravity, salinity, velocity, heat flow, and optical devices; limitations on these devices imposed by ocean environments; signal conditioning and recording; noise, sensitivity, and sampling limitations; and standards. Lectures by experts cover the principles of state-of-the-art systems being used in physical oceanography, geophysics, submersibles, acoustics. For lab work, day cruises in local waters allow students to prepare, deploy and analyze observations from standard oceanographic instruments.

Studies the principles of deterministic optimal control. Variational calculus and Pontryagin's maximum principle. Applications of the theory, including optimal feedback control, time-optimal control, and others. Dynamic programming and numerical search algorithms introduced briefly.

An introduction to pharmacology. Topics include mechanisms of drug action, dose-response relations, pharmacokinetics, drug delivery systems, drug metabolism, toxicity of pharmacological agents, drug interactions, and substance abuse. Selected agents and classes of agents examined in detail.

This course is an introduction to the design, analysis, and fundamental limits of wireless transmission systems. Topics to be covered include: wireless channel and system models; fading and diversity; resource management and power control; multiple-antenna and MIMO systems; space-time codes and decoding algorithms; multiple-access techniques and multiuser detection; broadcast codes and precoding; cellular and ad-hoc network topologies; OFDM and ultrawideband systems; and architectural issues.

Interpretations of the concept of probability. Basic probability rules; random variables and distribution functions; functions of random variables. Applications to quality control and the reliability assessment of mechanical/electrical components, as well as simple structures and redundant systems. Elements of statistics. Bayesian methods in engineering. Methods for reliability and risk assessment of complex systems, (event-tree and fault-tree analysis, common-cause failures, human reliability models). Uncertainty propagation in complex systems (Monte Carlo methods, Latin Hypercube Sampling). Introduction to Markov models. Examples and applications from nuclear and chemical-process plants, waste repositories, and mechanical systems. Open to qualified undergraduates.