The main goal of this course is to study the generalization ability of a number of popular machine learning algorithms such as boosting, support vector machines and neural networks. Topics include Vapnik-Chervonenkis theory, concentration inequalities in product spaces, and other elements of empirical process theory.

" This course covers a collection of geometric techniques that apply broadly in modern algorithm design."

We will discuss numerous research problems that are related to the internet. Sample topics include: routing algorithms such as BGP, communication protocols such as TCP, algorithms for intelligently selecting a resource in the face of uncertainty, bandwidth sensing tools, load balancing algorithms, streaming protocols, determining the structure of the internet, cost optimization, DNS-related problems, visualization, and large-scale data processing. The seminar is intended for students who are ready to work on challenging research problems. Each lecture will discuss: methods used today issues and problems formulation of concrete problems potential new lines of research A modest amount of background information will be provided so that the importance and context of the problems can be understood. No previous study of the internet is required, but experience with algorithms and/or theoretical computer science at the graduate/research level is needed.

The emergence of Western science: the systematization of natural knowledge in the ancient world, the transmission of the classical legacy to the Latin West, and the revolt from classical thought during the scientific revolution. Examines scientific concepts in light of their cultural and historical contexts.

This course introduces students to the technique of instrumental neutron activation analysis. This is a non-destructive analytical technique for the determination of elemental abundances at very low levels in a wide variety of samples, geological to biological.

The emphasis of this course is to use Trace Element Geochemistry to understand the origin and evolution of igneous rocks. The approach is to discuss the parameters that control partitioning of trace elements between phases and to develop models for the partitioning of trace elements between phases in igneous systems, especially between minerals and melt. Subsequently, published papers that are examples of utilizing Trace Element Geochemistry are read and discussed.

This course in Training Methods and Continuing Education for Health Workers identifies the role of training and continuing education as an important component of health service and personnel management. Participants will be guided through the steps of planning training and continuing education activities for a range of health workers from managers to village volunteers. The course draws on real life examples from community-directed onchocerciasis control, village health worker programs, and patent medicine vendor training programs, to name a few. As a final project, participants will prepare a training plan that includes needs assessment instruments, procedures for involving the trainees in their own learning, instructional objectives, appropriate learning methods and delivery modes, resource and budget needs, monitoring and evaluation mechanisms and follow-up supervision. Participants may wish to use the training guide they develop for this course as a foundation for an MPH CAPSTONE project. Please contact the instructor for details.

Solid-state diffusion, homogeneous and heterogeneous chemical reactions, and spinodal decomposition. Heat conduction in solids, convective and radiative heat transfer boundary conditions. Fluid dynamics, 1-D solutions to the Navier-Stokes equations, boundary layer theory, turbulent flow, and coupling with heat conduction and diffusion in fluids to calculate heat and mass transfer coefficients.

" This class serves as an introduction to mass transport in environmental flows, with emphasis given to river and lake systems. The class will cover the derivation and solutions to the differential form of mass conservation equations. Class topics to be covered will include: molecular and turbulent diffusion, boundary layers, dissolution, bed-water exchange, air-water exchange and particle transport."

This course addresses the design of tribological systems: the interfaces between two or more bodies in relative motion. Fundamental topics include: geometric, chemical, and physical characterization of surfaces; friction and wear mechanisms for metals, polymers, and ceramics, including abrasive wear, delamination theory, tool wear, erosive wear, wear of polymers and composites; and boundary lubrication and solid-film lubrication. The course also considers the relationship between nano-tribology and macro-tribology, rolling contacts, tribological problems in magnetic recording and electrical contacts, and monitoring and diagnosis of friction and wear. Case studies are used to illustrate key points.

This course describes the large-scale circulation systems of the tropical atmosphere and analyses the dynamics of such systems. Topics include: Radiative-convective equilibrium; the Hadley and walker circulation; monsoons; tropical boundary layers; theory of the response of the tropical atmosphere to localized sea-surface temperature anomalies; intraseasonal oscillations; equatorial waves; El Ni–o/Southern Oscillation; easterly waves; and tropical cyclones.

This course presents the phenomena, theory, and modeling of turbulence in the Earth's oceans and atmosphere. The scope ranges from the fine structure to planetary scale motions. The regimes of turbulence include homogeneous flows in two and three dimensions, geostrophic motions, shear flows, convection, boundary layers, stably stratified flows, and internal waves.

This course presents the phenomena, theory, and modeling of turbulence in the Earth's oceans and atmosphere. The scope ranges from centimeter to planetary scale motions. The regimes of turbulence include homogeneous isotropic three dimensional turbulence, convection, quasi-geotropic turbulence, shallow water turbulence, baroclinic turbulence, macro turbulence in the ocean and atmosphere.

Turbulent flows, with emphasis on engineering methods. Governing equations for momentum, energy, and species transfer. Turbulence: its production, dissipation, and scaling laws. Reynolds averaged equations for momentum, energy, and species transfer. Simple closure approaches for free and bounded turbulent shear flows. Applications to jets, pipe and channel flows, boundary layers, buoyant plumes and thermals, and Taylor dispersion, etc., including heat and species transport as well as flow fields. Introduction to more complex closure schemes, including the k-epsilon, and statistical methods in turbulence.

This seminar provides a deeper understanding of the post-translational mechanisms evolved by eukaryotic cells to target proteins for degradation. Students learn how proteins are recognized and degraded by specific machinery (the proteasome) through their previous tagging with another small protein, ubiquitin. Additional topics include principles of ubiquitin-proteasome function, its control of the most important cellular pathways, and the implication of this system in different human diseases. Finally, speculation on the novel techniques that arose from an increased knowledge of the ubiquitin-proteosome system and current applications in the design of new pharmacological agents to battle disease is also covered.

This course is offered to graduates and addresses issues regarding ultrafast optics. Topics covered include: generation and propagation of ultrashort pulses (nano-, pico-, femto-, attosecond pulses) and linear and non-linear effects. Applications of the topic vary and include high precision measurements, nonlinear optics, optical signal processing, optical communications, and x-ray generation.

The primary objective of this content is to prepare students to read and interpret cost-effectiveness studies. The students will first be introduced to basic economic concepts that are needed in order to understand the recommendations from the United States Panel on Cost Effectiveness in Health and Medicine. One example is the distinction between opportunity costs and budgetary costs. The recommendations will then be reviewed, particularly as they apply to what students should expect to read in cost-effectiveness research reports. Next, the relationship between cost-effectiveness results and other elements of the health care policy decision-making process will be discussed. More information will be provided on several aspects of how to conduct cost-effectiveness analyses. A critical discussion of several current articles demonstrating cost-effectiveness analyses will be an integral part of this course. When a student has completed this course, he or she will be able to read, comprehend, and perform a basic critique of cost-effectiveness papers and take part in discussions of planned cost-effectiveness research.

This course explores the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

The basic objective of Unified is to give a solid understanding of the fundamental disciplines of aerospace engineering, as well as their interrelationships and applications. These disciplines are Materials and Structures (M); Computers and Programming (C); Fluid Mechanics (F); Thermodynamics and Propulsion (T); and Signals and Systems (S). In choosing to teach these subjects in a unified manner, we seek to explain the common intellectual threads in these disciplines, as well as their combined application to solve engineering Systems Problems (SP). Throughout the year we will endeavor to point out the connections among the disciplines.

The design of urban environments. Strategies for change in large areas of cities, to be developed over time, involving different actors. Fitting forms into natural, man-made, historical, and cultural contexts; enabling desirable activity patterns; conceptualizing built form; providing infrastructure and service systems; guiding the sensory character of development. Involves architecture and planning students in joint work; requires individual designs or design and planning guidelines.