Covers modern tools and methods for product design and development. The cornerstone is a project in which teams of management, engineering, and industrial design students conceive, design, and prototype a physical product. Class sessions employ cases and hands-on exercises to reinforce the key ideas. Topics include: product planning, identifying customer needs, concept generation, product architecture, industrial design, concept design, and design-for-manufacturing.

Subject engages a dialogue with architecture and urbanism from the perspective of the visual artist. Ideas investigated thematically from early modernist practices to the most recent examples of contemporary production. Art making as an adjunct to the design process is challenged by both synthetic and critical models of production. Visual art practice is examined as a conceptual prologue to architectural and urbanistic thinking, as an integrated part of the design process, and as a critical epilogue. Lectures and discussions lead to the development of realized projects to be coordinated with architectural studio. This seminar engages in the notion of space from various points of departure. The goal is first of all to engage in the term and secondly to examine possibilities of art, architecture within urban settings in order to produce what is your interpretation of space.

Principles of functional, imperative, and logic programming languages. Meta-circular interpreters, semantics (operational and denotational), type systems (polymorphism, inference, and abstract types), object oriented programming, modules, and multiprocessing. Case studies of contemporary programming languages. Programming experience and background in language implementation required. From the course home page: The course involves substantial programming assignments and problem sets as well as a significant amount of reading. The course uses the SCHEME+ programming language for all of its assignments.

" This is an engineering laboratory subject for mechanical engineering juniors and seniors. Major emphasis is on interplay between analytical and experimental methods in solution of research and development problems. Communication (written and oral) of results is also a strong component of the course. Groups of two or three students work together on three projects during the term."

Engineering laboratory subject for mechanical engineering juniors and seniors. Major emphasis on interplay between analytical and experimental methods in solution of research and development problems. Communication (written and oral) of results is also a strong component of the course. Groups of two or three students work together on three projects during the term. This is an engineering laboratory subject for mechanical engineering juniors and seniors. Major emphasis is on interplay between analytical and experimental methods in solution of research and development problems. Communication (written and oral) of results is also a strong component of the course.

Seminar covering topics of current interest in biology. Includes reading and analysis of research papers and student presentations. Contact Biology Education Office for topics. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. The instructor for this course, Dr. Kosinski-Collins, is a member of the HHMI Education Group. Maintenance of the complex three-dimensional structure adopted by a protein in the cell is vital for function. Oftentimes, as a consequence of environmental stress, genetic mutation, and/or infection, the folded structure of a protein gets altered and multiple proteins stick and fall out of solution in a process known as aggregation. In many protein aggregation diseases, incorrectly folded proteins self-associate, forming fiber-like aggregates that cause brain cell death and dementia. In this course, the molecular and biochemical basis of the prion diseases, which include bovine spongiform encephalopathy (mad cow disease), Creutzfedt-Jakob disease and kuru will be examined. Also discussed are other classes of misfolding diseases such as Alzheimer's disease and Huntington's disease. The proteins involved in all of these disorders and how the proteins' three dimensional structures change during the course of these afflictions is covered as well as why prions from certain species cannot infect animals from other species based on protein sequence and structure. The course will then address possible detection methods and therapies that are under development to treat some of the protein aggregation diseases.

Subject assesses the relationships between sequence, structure, and function in complex biological networks as well as progress in realistic modeling of quantitative, comprehensive functional-genomics analyses. Topics include: algorithmic, statistical, database, and simulation approaches; and practical applications to biotechnology, drug discovery, and genetic engineering. Future opportunities and current limitations critically assessed. Problem sets and project emphasize creative, hands-on analyses using these concepts.

Principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Mass transport through membranes: diffusion, osmosis, chemically mediated, and active transport. Electric properties of cells: ion transport; equilibrium, resting, and action potentials. Kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the concepts. For juniors and seniors. Students engage in extensive written and oral communication exercises.

" This course develops logical, empirically based arguments using statistical techniques and analytic methods. Elementary statistics, probability, and other types of quantitative reasoning useful for description, estimation, comparison, and explanation are covered. Emphasis is on the use and limitations of analytical techniques in planning practice."

Introduction to the application of elementary statistics to political analysis. A basic literacy subject, teaching the student how to read and interpret the quantitative literature in various subfields of political science and public policy. Students develop elementary statistical computation skills and learn to use a statistical computing package. From the course home page: This course provides students with a rigorous introduction to Statistics for Political Science. Topics include basic mathematical tools used in social science modeling and statistics, probability theory, theory of estimation and inference, and statistical methods, especially differences of means and regression. The course is often taken by students outside of political science, especially those in business, urban studies, and various fields of public policy, such as public health. Examples draw heavily from political science, but some problems come from other areas, such as labor economics.

This course examines quantum computation and quantum information. Topics include quantum circuits, quantum Fourier transform and search algorithms, physical implementations, the quantum operations formalism, quantum error correction, stabilizer and Calderbank-Shor-Steans codes, fault tolerant quantum computation, quantum data compression, entanglement, and proof of the security of quantum cryptography. Prior knowledge of quantum mechanics and basic information theory is required.

Together, this course and 8.06 Quantum Physics III cover quantum physics with applications drawn from modern physics. Topics covered in this course include the general formalism of quantum mechanics, harmonic oscillator, quantum mechanics in three-dimensions, angular momentum, spin, and addition of angular momentum.

8.06 is the third course in the three-sequence physics undergraduate Quantum Mechanics curriculum. By the end of this course, you will be able to interpret and analyze a wide range of quantum mechanical systems using both exact analytic techniques and various approximation methods. This course will introduce some of the important model systems studied in contemporary physics, including two-dimensional electron systems, the fine structure of Hydrogen, lasers, and particle scattering.

Experimental basis of quantum physics: photoelectric effect, Compton scattering, photons, Franck-Hertz experiment, the Bohr atom, electron diffraction, deBroglie waves, and wave-particle duality of matter and light. Introduction to wave mechanics: Schroedinger's equation, wave functions, wave packets, probability amplitudes, stationary states, the Heisenberg uncertainty principle and zero-point energies. Solutions to Schroedinger's equation in one dimension: transmission and reflection at a barrier, barrier penetration, potential wells, the simple harmonic oscillator. Schroedinger's equation in three dimensions: central potentials, and introduction to hydrogenic systems.

A two-semester subject on quantum theory, stressing principles: uncertainty relation, observables, eigenstates, eigenvalues, probabilities of the results of measurement, transformation theory, equations of motion, and constants of motion. Symmetry in quantum mechanics, representations of symmetry groups. Variational and perturbation approximations. Systems of identical particles and applications. Time-dependent perturbation theory. Scattering theory: phase shifts, Born approximation. The quantum theory of radiation. Second quantization and many-body theory. Relativistic quantum mechanics of one electron. This is the second semester of a two-semester subject on quantum theory, stressing principles. Topics covered include: time-dependent perturbation theory and applications to radiation, quantization of EM radiation field, adiabatic theorem and Berry's phase, symmetries in QM, many-particle systems, scattering theory, relativistic quantum mechanics, and Dirac equation.

" This course introduces the students to dynamics of large-scale circulations in oceans and atmospheres. Basic concepts include mass and momentum conservation, hydrostatic and geostrophic balance, and pressure and other vertical coordinates. It covers the topics of fundamental conservation and balance principles for large-scale flow, generation and dissipation of quasi-balanced eddies, as well as equilibrated quasi-balanced systems. Examples of oceanic and atmospheric quasi-balanced flows, computational models, and rotating tank experiments can be found in the accompaniment laboratory course 12.804, Large-scale Flow Dynamics Lab."

Seminar covering topics of current interest in biology. Includes reading and analysis of research papers and student presentations. Contact Biology Education Office for topics. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. To understand and treat any disease with a genetic basis or predisposition, scientists and clinicians need effective ways of manipulating the levels of genes and gene products. Conventional methods for the genetic modification of many experimental organisms are technically demanding and time consuming. Just over 5 years ago, a new mechanism of gene-silencing, termed RNA interference (RNAi), was discovered. In addition to being a fascinating biological process, RNAi provides a revolutionary technology that has already changed the way biomedical research is done and that may even prove useful for genetic interventions in a clinical context. In this course, students learn how RNAi was discovered, how it works, and what its physiological relevance might be. How RNAi can be harnessed to modulate gene expression and perform genetic screens, both in cells and in various organisms is also covered. Finally, this course examines the first attempts to use RNAi for the treatment of models of human diseases in experimental animals.

This course will start with a survey of basic oxygen radical biochemistry followed by a discussion of the mechanisms of action of cellular as well as dietary antioxidants. After considering the normal physiological roles of oxidants, we will examine the effects of elevated ROS and a failure of cellular redox capacity on the rate of organismal and cellular aging as well as on the onset and progression of several major diseases that are often age-related. Topics will include ROS-induced effects on stem cell regeneration, insulin resistance, heart disease, neurodegenerative disorders, and cancer. The role of antioxidants in potential therapeutic strategies for modulating ROS levels will also be discussed.This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Laboratory or field work in earth, atmospheric, and planetary sciences. To be arranged with department faculty. Consult with department Education Office. This course introduces fundamentals of radon physics, geology, radiation biology; provides hands on experience of measurement of radon in MIT environments, and discusses current radon research in the fields of geology, environment, building and construction, medicine and health physics.